Plasma viral load in HIV-1 and HIV-2 singly and dually infected individuals in Guinea-Bissau, West Africa: significantly lower plasma virus set point in HIV-2 infection …

S Andersson, H Norrgren, Z da Silva… - Archives of internal …, 2000 - jamanetwork.com
Background The intriguing differences in the natural course, transmissibility, and
epidemiological characteristics of human immunodeficiency virus type 1 (HIV-1) and HIV-2
are still insufficiently explained. Differences in plasma viral load are an obvious possibility,
but this has been difficult to investigate because of the lack of tests for HIV-2 RNA. Objective
To compare plasma HIV RNA load between individuals infected with HIV-1 and HIV-2 in
Guinea-Bissau, a West African country with high prevalence and incidence of HIV-1 and HIV …