“Ragged-red” fibres in myotonic dystrophy
S Ono, H Kurisaki, K Inouye, T Mannen - Journal of the neurological …, 1986 - Elsevier
Twenty-five muscle biopsies (18 from the left biceps and 7 from the left quadriceps) of 25
patients suffering from myotonic dystrophy (MyD) were studied, 13 of which showed “ragged-
red” fibres (RRFs); all the RRFs, which were type I fibres, were found in biceps muscles,
while none of the quadriceps muscles showed RRFs. The incidence of RRFs varied from
0.5% to 20.0%(average 4.2%). On electron microscopy, RRFs contained enlarged
mitochondria, usually in subsarcolemmal clusters, including dense granular matrix …
patients suffering from myotonic dystrophy (MyD) were studied, 13 of which showed “ragged-
red” fibres (RRFs); all the RRFs, which were type I fibres, were found in biceps muscles,
while none of the quadriceps muscles showed RRFs. The incidence of RRFs varied from
0.5% to 20.0%(average 4.2%). On electron microscopy, RRFs contained enlarged
mitochondria, usually in subsarcolemmal clusters, including dense granular matrix …
