Neuronal control of acetylcholine receptor turnover rate at a vertebrate neuromuscular junction
TA Levitt, RH Loring, MM Salpeter - Science, 1980 - science.org
TA Levitt, RH Loring, MM Salpeter
Science, 1980•science.orgThe turnover rate of acetylcholine receptors at neuromuscular junctions in mice increases
progressively after denervation and, after 15 days, reaches a half-time of 30±5 hours.
Denervation thus causes the clustered junctional acetylcholine receptors to assume the
rapid turnover characteristic of extrajunctional receptors before innervation.
progressively after denervation and, after 15 days, reaches a half-time of 30±5 hours.
Denervation thus causes the clustered junctional acetylcholine receptors to assume the
rapid turnover characteristic of extrajunctional receptors before innervation.
The turnover rate of acetylcholine receptors at neuromuscular junctions in mice increases progressively after denervation and, after 15 days, reaches a half-time of 30 ± 5 hours. Denervation thus causes the clustered junctional acetylcholine receptors to assume the rapid turnover characteristic of extrajunctional receptors before innervation.
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