The incidence and risk factors of post-infectious irritable bowel syndrome: a meta-analysis.
C Dai, M Jiang - Hepato-gastroenterology, 2012 - europepmc.org
C Dai, M Jiang
Hepato-gastroenterology, 2012•europepmc.orgResults Ten studies were assessed for incidence of PI-IBS at last study assessment (POR=
6.03; 95% CI 3.58 to 10.13). In subgroup analysis, six studies each were assessed for
incidence of PI-IBS at 3 months (POR= 8.47; 95% CI 4.85 to 14.76), 6 months (POR= 4.58;
95% CI 2.94 to 7.14) and 12 months (POR= 6.19; 95% CI 2.82 to 13.58). Four studies were
assessed for incidence of PI-IBS at 24-36 months (POR= 4.05; 95% CI 3.13 to 5.24).
Conclusions The odds of developing IBS are increased after acute gastrointestinal infection …
6.03; 95% CI 3.58 to 10.13). In subgroup analysis, six studies each were assessed for
incidence of PI-IBS at 3 months (POR= 8.47; 95% CI 4.85 to 14.76), 6 months (POR= 4.58;
95% CI 2.94 to 7.14) and 12 months (POR= 6.19; 95% CI 2.82 to 13.58). Four studies were
assessed for incidence of PI-IBS at 24-36 months (POR= 4.05; 95% CI 3.13 to 5.24).
Conclusions The odds of developing IBS are increased after acute gastrointestinal infection …
Results
Ten studies were assessed for incidence of PI-IBS at last study assessment (POR= 6.03; 95% CI 3.58 to 10.13). In subgroup analysis, six studies each were assessed for incidence of PI-IBS at 3 months (POR= 8.47; 95% CI 4.85 to 14.76), 6 months (POR= 4.58; 95% CI 2.94 to 7.14) and 12 months (POR= 6.19; 95% CI 2.82 to 13.58). Four studies were assessed for incidence of PI-IBS at 24-36 months (POR= 4.05; 95% CI 3.13 to 5.24).
Conclusions
The odds of developing IBS are increased after acute gastrointestinal infection. There are many risk factors for the development of PI-IBS including female gender, younger age, severity of the initial gastrointestinal insult, duration of the enteritis and adverse psychological factors.
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