Renal improvement in myeloma with bortezomib plus plasma exchange
BL Burnette, N Leung… - New England Journal of …, 2011 - Mass Medical Soc
BL Burnette, N Leung, SV Rajkumar
New England Journal of Medicine, 2011•Mass Medical SocRenal Improvement in Myeloma with Bortezomib plus Plasma Exchange Page 1 correspondence
n engl j med 364;24 nejm.org june 16, 2011 2365 Renal Improvement in Myeloma with
Bortezomib plus Plasma Exchange To the Editor: There is conflicting evidence on the benefit of
plasma exchange to quickly reduce the level of serum free light chains and reverse acute renal
failure associated with myeloma cast nephropathy.Such data are limited, since studies were
conducted before the arrival of new agents, such as bortezomib, and serum assays for free light …
n engl j med 364;24 nejm.org june 16, 2011 2365 Renal Improvement in Myeloma with
Bortezomib plus Plasma Exchange To the Editor: There is conflicting evidence on the benefit of
plasma exchange to quickly reduce the level of serum free light chains and reverse acute renal
failure associated with myeloma cast nephropathy.Such data are limited, since studies were
conducted before the arrival of new agents, such as bortezomib, and serum assays for free light …
The acute renal failure that can complicate myeloma can affect survival. The combination of bortezomib and plasma exchange to remove light chains from the circulation can have a beneficial effect on renal function.
The New England Journal Of Medicine