Increased level of polymerase III transcribed Alu RNA in hepatocellular carcinoma tissue
RB Tang, HY Wang, HY Lu, J Xiong… - … in cooperation with …, 2005 - Wiley Online Library
RB Tang, HY Wang, HY Lu, J Xiong, HH Li, XH Qiu, HQ Liu
Molecular Carcinogenesis: Published in cooperation with the …, 2005•Wiley Online LibraryThere have been extensive observations that RNA containing repetitive elements
accumulates in transformed cells and tumor tissues. In the present study, we first obtained
result consistent with previous observations by in situ hybridization. Then we used primer
extension analysis to determine the level of polymerase III directed Alu RNA and found an
increased expression of Alu RNA in hepatocellular carcinoma.© 2004 Wiley‐Liss, Inc.
accumulates in transformed cells and tumor tissues. In the present study, we first obtained
result consistent with previous observations by in situ hybridization. Then we used primer
extension analysis to determine the level of polymerase III directed Alu RNA and found an
increased expression of Alu RNA in hepatocellular carcinoma.© 2004 Wiley‐Liss, Inc.
Abstract
There have been extensive observations that RNA containing repetitive elements accumulates in transformed cells and tumor tissues. In the present study, we first obtained result consistent with previous observations by in situ hybridization. Then we used primer extension analysis to determine the level of polymerase III directed Alu RNA and found an increased expression of Alu RNA in hepatocellular carcinoma. © 2004 Wiley‐Liss, Inc.
Wiley Online Library