There are reports of adverse effects of cannabinoids on pregnancy outcome including
retarded embryo development and pregnancy failure. Thus, discoveries of endogenous
cannabinoid-like lipid mediators and cannabinoid receptors raise questions about their
pathophysiological roles during normal pregnancy. We previously reported that
anandamide, an endogenously produced arachidonate derivative (endocannabinoid), is
synthesized in the female reproductive tracts, and it acts on cannabinoid receptors …